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HIV REVERSE TRANSCRIPTASE
Descriptors Found:
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DeCS
Descriptor
English
:
HIV Reverse Transcriptase
Descriptor
Spanish
:
Transcriptasa Inversa del VIH
Descriptor
Portuguese
:
Transcriptase Reversa do HIV
Tree Number:
D08.811.913.696.445.308.300.750.187
D12.776.964.775.375.545.875
D12.776.964.775.375.750.187
D12.776.964.775.562.875.875
D12.776.964.970.600.850.375.545.875
D12.776.964.970.600.850.375.750.187
Definition
English
:
A reverse transcriptase encoded by the POL GENE of
HIV
. It is a heterodimer of 66 kDa and 51 kDa subunits that are derived from a common precursor protein. The heterodimer also includes an RNAse H activity (RIBONUCLEASE H, HUMAN IMMUNODEFIENCY VIRUS) that plays an essential
role
the viral replication process.
History Note
English
:
2008
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
52726
Unique Identifier:
D054303
Occurrence in VHL
:
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